| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d3fe7dc6459c64519c27abf0d5fe11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
| filingDate |
2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ec476809677c2d2183572291e5aaf16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc8664a228bc3710b6c0fa851a72234c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_798cedc83c3a57c8d212b27acde83dd2 |
| publicationDate |
2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112015023168-B1 |
| titleOfInvention |
COMPOSITION OF 3,6-BIS(N-FUMARYL-4-AMINOBUTYL)-2,5-CRYSTALLINE DICETOPIPERAZINE, METHOD OF PRODUCTION OF 3,6-BIS(N-FUMARYL-4-AMINOBUTYL)-2,5-DICETOPIPERAZINE PARTICLES AND USE OF A CRYSTALLINE DICETOPIPERAZINE COMPOSITION |
| abstract |
CRYSTALLINE DICETOPIPERAZINE COMPOSITION, METHODS OF PRODUCTION OF DICETOPIPERAZINE PARTICLES, PRODUCTION OF A COMPOSITION, AND TREATMENT AND USE OF A CRYSTALLINE DICETOPIPERAZINE COMPOSITION. The present document discloses DKP microcrystals produced by an improved method in which they are not irreversibly self-assembled into microparticles. The microcrystals can be dispersed by atomization and re-formed by spray drying into particles having spherical shell morphology. Active agents and excipients can be incorporated into the particles by spray drying a solution containing the components to be incorporated into the microcrystalline diketopiperazine particles. In particular, microcrystalline particle compositions are suitable for pulmonary drug delivery of one or more peptides, proteins, nucleic acids and/or small organic molecules. |
| priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |