abstract |
COMPOSITIONS AND METHODS FOR USES OF NUCLEIC ACID TARGETING NUCLEIC ACID, VECTOR, SUCH NUCLEIC ACID, AND STOCHIOMETRIC DELIVERY COMPLEX. The present invention relates to compositions and methods for using nucleic acid targeting nucleic acids and complexes thereof. Genome engineering can refer to the alteration of the genome through the deletion, insertion, mutation or substitution of specific nucleic acid sequences. The change may be gene or site specific. Genome engineering can use nucleases to cut a nucleic acid in this way generating a site for the alteration. Non-genomic nucleic acid engineering is also understood. |