Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ca0841c52dc980c3f201762d410f79b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ffd5528fd07384d7b07ab484ed5b143 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d6f2b5f6a734a42c6d992ff3d922cc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_191a2d38f308c6a65db53a747ffa10e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25448013973162d96cbcc33a53e39181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_247c353a852a1268a9c80cadf29f4f0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5de58cc759ba0bfd826330b50d819de |
publicationDate |
2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
BR-112015021414-B1 |
titleOfInvention |
newcastle disease virus and its uses |
abstract |
newcastle disease virus and its uses The invention relates to the chimeric newcastle disease virus genetically modified to express an agonist of an immune cell co-stimulating signal and compositions comprising such viruses. the invention also relates to a chimeric newcastle disease virus genetically modified to express an antagonist of an immune cell inhibitory signal and compositions comprising such viruses. the chimeric newcastle disease virus and the compositions are useful in the treatment of cancer. moreover, the invention provides methods of treating cancer comprising administering the newcastle disease virus in combination with a co-stimulating signal agonist to an immune cell and / or an inhibiting signal antagonist to an immune cell. |
priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |