| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bfd0f9b2b07ba3b07da97df27778a31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-112 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 |
| filingDate |
2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ec19a52360073fb11edec5350c90282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c981ee549d8e099ed0d35030121b54ec |
| publicationDate |
2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112015020439-A2 |
| titleOfInvention |
bone replacement material for bone and dental surgery and preparation process of a bone replacement material |
| abstract |
Abstract "Bone Replacement Material for Bone and Dental Surgery and Process for Preparation of a Bone Replacement Material" The invention is directed to a bone replacement material for bone and dental surgery, comprising: i) a solid base support of at least one phosphocalcic compound having free hydroxyl moieties on the surface, and ii) an amount of a bmp-2 human protein mimetic peptide having a sequence kx1pkx2z1z2x3ptex4saismlyl where x1, x2, x3 and x4 are non-amino acids. identical or different polar and identical or different z1 and z2 denote a cysteine or serine residue, said amount of bmp-2 protein mimetic peptide being covalently grafted at its n-terminal end to the level of said clusters hydroxyls having a density of less than 100.10-12 mol / mm2 surface of the solid support. The material whose osteoinductive properties are expressed quickly and intensely finds its application in all areas of bone surgery. A process of manufacturing material with a controlled graft density is also claimed. |
| priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |