| abstract |
Abstract "Topical aqueous ophthalmic compositions containing a 1h-indol-1-carboxamide derivative and use thereof for the treatment of ophthalmic disease". The present invention is directed to the provision of a multidose topical ophthalmic composition containing a 1h-indole-1-carboxamide and its use for the treatment of ophthalmic disease. more specifically the present invention is directed to a multidose aqueous ophthalmic composition (e.g., a solution, a suspension, an emulsion or the like) containing a 1h-indol-1-carboxamide (e.g. n- (1-methyl-5- (trifluoromethyl) -1h-pyrazol-3-yl) -5 - ((6 - ((methylamino) methyl) pyrimidin-4-yl) oxy) -1h-indol-1-carboxamide) and use thereof for the treatment of an ophthalmic disease in the back of the eye such as age-related macular degeneration (amd). |