abstract |
CRYSTALLINE FORM OF THE COMPOUND USED AS A MINERALOCORTICOID RECEPTOR ANTAGONIST AND METHOD FOR THEIR PREPARATION. The present invention pertains to the technical field of medicaments, and relates to a crystalline form of a compound used as a mineralocorticoid receptor antagonist and a method for its preparation, and in particular, a method for the preparation of a compound 2-chloro-4-[(3S,3aR)-3-cyclopentyl-7-(4-hydroxypiperidine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinoline -2-yl]benzonitrile of formula (I), a crystalline form thereof, a method of preparation for the crystalline form, and the use of the crystalline form in the preparation of medicaments for the treatment and/or prevention of kidney damage or cardiovascular diseases. |