| abstract |
Summary "Substituted Oxazolidinones Aldehyde Derivative" Formula (b) The present invention relates to 5-chloro-n - ({(5s) -2-oxo-3- [4- (3-oxo-morpholin-4-yl) ) phenyl] -1,3-oxazolidin-5-yl} methyl) thiophene-2-carboxamide, specifically rivaroxaban, to the processes for its preparation, as well as its application in the treatment and / or prophylaxis of diseases, especially thromboembolic disorders. the prodrug of the compound of formula (b) is chemically termed as 5-chloro-n-formyl-n - ({(5s) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl ] -1,3-oxazolidin-5-yl} methyl) thiophene-2-carboxamide (i). |