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filingDate 2013-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112015005937-A2
titleOfInvention chromatographic media and devices
abstract "chromatographic media and devices" chromatographic devices containing chromatographic media and methods of production and methods of use of chromatographic devices. Chromatographic devices enable more efficient, productive and / or environmentally safe chromatographic operation due to one or more of the following advantages over conventional chromatographic operations: elimination of a device packaging step by the user; elimination of clean-in-place steps (cip); elimination of clean-in-place (cip) steps using sodium hydroxide solution; elimination of any validation steps by the user; and use of a chromatographic device comprising biodegradable material. the chromatographic medium includes porous inorganic particles having a functionalized surface and a median pore size of at least about 300 angstroms (å) or at least about 300 å to about 3000 å. the inorganic particles may have a bet surface area of at least about 20 m2 / g or at least about 25 m2 / g or about 30 m2 / g to about 2000 m2 / g.
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