| abstract |
METHODS FOR DISTINGUISHING A POLYNUCLEOTIDE TARGET, FOR CONTROLLING THE MOTION OF A POLYNUCLEOTIDE, CONSTRUCT, SENSOR TO DISTINGUISH A POLYNUCLEOTIDE THE TARGET, USE OF A CONSTRUCT, KIT, AND, APPARATUS TO DISTINGUISH POLYNUCLEOTIDE TARGETS IN A SAMPLE The invention relates to methods using constructs comprising a helicase and an additional polynucleotide agglutination moiety. The helicase is attached to the agglutination moiety of the polynucleotide and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly used for polynucleotide sequencing. |