abstract |
NEPRYLYSIN INHIBITORS. In one aspect, the invention relates to compounds having formula XII: wherein Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds described herein are prodrugs of compounds that have neprilysin inhibiting activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using such compounds; and processes and intermediates for preparing these compounds. |