abstract |
1 / 1 abstract “compounds, and pharmaceutical composition†the invention provides modulators for the orphan nuclear receptor rorî³ and methods for the treatment of diseases mediated by rorî³ for administering these new rorî³ modulators to a human being or a mammal that needs it. specifically, the present invention provides a carboxamide or sulfonamide containing cyclic compounds of formula (1), (1'), (100), (100'), (200) and (200'), and the enantiomers, diastereoisomers, tautomers, n-oxides, solvates and the pharmaceutically acceptable salts thereof. |