abstract |
COMPOUND OF FORMULA (I), FORMULA (11) OR FORMULA (111), PHARMACEUTICAL COMPOSITION, METHOD FOR TREATMENT OF A CONDITION OR DISORDER IN WHICH TTX-S CHANNEL BLOCKERS ARE INVOLVED, COMPOSED OF ANY OF THE FORMULA OR A PRO- DRUG THEREOF OR A PHARMACEUTICALLY ACCEPTABLE SALT AND PROCESS FOR PREPARING A PHARMACEUTICAL COMPOSITION. The present invention relates to pyrrolopyridinone derivatives which have voltage-gated sodium channel blocking activities such as TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage-gated sodium channels are involved . The invention also relates to pharmaceutical compositions comprising such compounds and the use of such compounds and compositions in the prevention or treatment of such diseases in which voltage-gated sodium channels are involved. |