| abstract |
arginase inhibiting compound, pharmaceutical composition and use of the compound. boronic acid analogs of the invention are potent inhibitors of arginase i and arginase ii activity. these compounds are candidates for therapeutic agents for the treatment of a disease or disorder that correlates with an imbalance in the activity or concentration of the cellular enzymes arginase i and ii. the invention also provides pharmaceutical compositions of the compounds of the invention and methods for using the compositions in therapy. |