| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79395586b9d970526ce3a97d79569e98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19b911329515bce4551d2abab027f0c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b72e06bdfa3407cac2b39432a2a9fc8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1793
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 |
| filingDate |
2012-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bd67b25b8d56593f68e8a31bb1541ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c01522cd7ea58399ef95da49817adef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9880a3d59c13ca2926b35f5694a9b93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fec9cf9e3356cd2f93c0256a33b07cf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_592f8ef8ae330f4bd6d0a4edf48e9edc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c313036922907bf9d9c4d80e59509a |
| publicationDate |
2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112014024398-B1 |
| titleOfInvention |
POLYPEPTIDE BINDING HUMAN RANKL, THERAPEUTIC COMPOSITIONS COMPRISING SAID POLYPEPTIDE, ISOLATED NUCLEIC ACID, EXPRESSION VECTOR AND THERAPEUTIC USE OF SAID POLYPEPTIDE |
| abstract |
OSTEOPROTEGERIN DERIVED COMPOSITION AND USE THEREOF A therapeutic composition is disclosed that can be used for the treatment or prevention of diseases in association with bone resorption, particularly of a metastatic carcinoma. In certain aspects, the composition is based on a polypeptide that includes the 215 major amino acids of human osteoprotegerin followed by the Fc portion of the human IgG1 protein. Expression vectors and DNA expression systems to overproduce the polypeptide in mammalian cells are also produced. |
| priorityDate |
2012-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |