abstract |
1,3-diphenylpropane derivatives, preparations and uses thereof. the present invention relates to new 1,3-diphenylpropane derivatives, pharmaceutical compositions comprising them and their therapeutic uses, in particular, in the fields of human and animal health. the compounds according to the present invention have intrinsic ppar agonist properties. these are therefore of particular interest in the treatment of metabolic and/or inflammatory diseases and particularly peripheral and central diseases associated with the metabolic syndrome, such as various forms of steatohepatitis, type 2 diabetes, various neurodegenerative disorders such as Alzheimer's disease , Parkinson's disease and multiple sclerosis. |