| abstract |
DISUBSTITUTED BENZOTHIENYL-PYROLOTRIAZINES AND THEIR USES. The present invention relates to novel substituted 5-(1-benzothiophen-2-yl)-pyrrolo[2,1-f][1,2,4]triazine-4-amine derivatives which have a tyrosine-4-amine inhibitory activity. protein kinase, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment of proliferative disorders, in particular cancer and tumor diseases. |