abstract |
Patents for the preparation of 5- [2- [7- (trifluoromethyl) -5- [4- (trifluoromethyl) phenyl] pyrazol [1,5-a] pyrimidin-3-yl] ethynyl] 2-pyridinamine ". The present invention relates to methods for preparing 5- [2- [7- (trifluoromethyl) -5- [4- (trifluoromethyl) phenyl] pyrazolo [1,5-a] pyrimidin-3-yl] ethynyl] -2 -pyridinamine (compound a), which is useful for treating depression and other disorders of cns. The present methods are useful for preparing the compound at large scale in production laboratories. |