http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112014007718-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate | 2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da7bc85697709880fa3719b354e764d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a10bb03aa4d14c57ae020c77fee6e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e655160e3a07046c33f612ddb0acdd85 |
| publicationDate | 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-112014007718-B1 |
| titleOfInvention | METHOD FOR PREPARING 1-(4-(4-(3,4-DICHLORO-2-FLUOROPHENYLAMINO)-7-METHOXYQUINAZOLIN-6-ILOXY)PIPERIDIN-1-IL)-PROP-2-EN-1-ONE E INTERMEDIARIES USED IN THE SAME |
| abstract | method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-prop-2-en-1-one hydrochloride and intermediaries used in it. the present invention relates to an improved method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-prop-2 hydrochloride -en-1-one, which selectively and efficiently inhibits the development of cancer cells induced by overexpression of an epidermal development factor receptor (egfr) and prevents the development of drug resistance caused by a tyrosine kinase mutation , and intermediaries used in it. |
| priorityDate | 2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.