| abstract |
nanoparticulate phosphate adsorbent based on magma or magma / magnetite, production and their uses the present invention relates to a phosphate sorbent based on magma or magma / magnetite comprising (i) an iron oxide core comprising a structure reverse spinel iron oxide crystal, (ii) a coating selected from monomeric carbohydrates, specifically monosaccharides or disaccharides, alditols or mixtures thereof, and / or (iii) a pharmaceutical excipient selected from polymeric carbohydrates, characterized by the fact that the phosphate adsorbent is in the form of nanoparticles with an iron oxide (i) core particle size less than 20 nm. the present invention further relates to a method for the production of a phosphate adsorbent based on magma or magma / magnetite, to pharmaceutical compositions comprising the phosphate sorbent, and to its medical uses, especially for the prevention and / or treatment of hyperphosphatemia. |