abstract |
abstract “capsule formulation comprising montelukast and levocetirizine” means a capsule formulation for the prevention or treatment of allergic rhinitis and asthma, which comprises two separate layers of: (1) a montelukast layer comprising montelukast or a pharmaceutically acceptable salt thereof; and (2) a levocetirizine layer comprising levocetirizine or a pharmaceutically acceptable salt thereof; and a method for preparing the same. The capsule formulation according to the present invention can completely separate the two active ingredients, thereby minimizing the reactivity between them and improving the stability of the product against the effects of aging, and thus, can optimize the therapeutic effects. |