| abstract |
Patent Summary: "Quinolinyl glucagon receptor modulators". The present invention relates to a compound of formula II or a pharmaceutically acceptable salt thereof, wherein R 1, R 2, R 3, A 1, A 2, A 3, B 1, B 2, B 3 and B 4 are as defined herein. The compounds of formula I have been found to act as glucagon antagonists or reverse agonists. therefore, the compounds of formula I and the pharmaceutical compositions thereof are useful for the treatment of glucagon mediated diseases, disorders, or conditions. |