abstract |
METHOD OF PRODUCTION OF POLYPLOIDIZED MEGAKYOCYTES, COMPOSITION OF BLOOD CELLS, METHOD OF PRODUCTION OF A PLATELET, PLATELET AND BLOOD PRODUCT. The present invention relates to a method of promoting megakaryocyte polyploidization and, therefore, megakaryocyte production. highly polyploided, a method of efficiently producing platelets from polyploidized megakaryocytes and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing the expression of an apoptosis suppressor gene in megakaryocytes prior to polyploidization and culturing the resulting cells. |