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filingDate 2012-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3721e2a447548374d11cbc0fe65f4637
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publicationDate 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112013025500-B8
titleOfInvention method to detect peptidoglycan (pgn) contamination of glucose polymers
abstract method to detect pro-inflammatory contaminants of glucose polymers. the invention relates to a method for detecting contaminants in glucose polymers, said contaminants having the ability to cause, separately or in combination, an inflammatory reaction, characterized in that it includes at least one in vitro inflammatory response test with the use of a cell line that allows at least one inflammatory response factor to be detected, the cell line being either a macrophage or a cell line with a differentiated macrophage or a cell that expresses one or more toll-like receptors (tlrs) or receptors of the nod type such as tlr2, tlr4 or nod2 and which allows the responses of the receiver (s) to be detected or a combination thereof.
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