abstract |
7-deazapurine and substituted purine compounds as epigenetic enzyme modulators. the present invention relates to substituted purine and 7-deazapurine compounds. the present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which dotll-mediated protein methylation plays a role, such as in cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to individuals in need thereof. . |