| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-25 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2011-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6044b1b3f940f9a2756aaeb01272f05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91224a4925413dac164105644d90e07a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699a6cec1348628feb079b4648d5f086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b90fa509bbccdad1fc13e100675c75b7 |
| publicationDate |
2016-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112013004585-A2 |
| titleOfInvention |
cationic lipid, lnp composition, and use of a cationic lipid |
| abstract |
cationic lipid, linp composition, and use of a cationic lipid. The present invention provides novel cationic lipids which may be used in combination with other lipid components, such as cholesterol and peg-lipids, to form lipid nanoparticles with oligonucleotides. It is an object of the present invention to provide a cationic lipid support that demonstrates improved efficiency associated with less liver toxicity due to lower liver lipid levels. The present invention employs low molecular weight cationic lipids with a short lipid chain to improve the efficiency and tolerability of in vivo distribution of rnasi. |
| priorityDate |
2010-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |