| abstract |
tetranectin-apolipoprotein a-i, lipid particles containing it for their use. disclosed herein is a lipid particle comprising an apolipoprotein, a phosphatidylcholine and a lipid such as a phospholipid, fatty acid or steroid lipid. In one embodiment, the lipid particle comprises only one apolipoprotein. In one embodiment, the lipid particle consists of an apolipoprotein, a phospholipid, a lipid, and a detergent. In one embodiment, lipid is a second phosphatodylcholine, wherein the first phosphotidylcholine and the second phosphotidylcholine differ in one or two fatty acid residues or fatty acid residue derivatives which are esterified to the phosphatidylcholine glycerol backbone. in one embodiment, apolipoprotein is selected from an apolipoprotein having the amino acid sequence selected from seq id: 01, 02, 06, 55 and 67, i.e. a variant thereof having at least 70% sequence identity with the selected sequence. |