| abstract |
method and apparatus for determining the content of protein bound and intermediate uremic toxins in a biological fluid. The present invention relates to a further method and device for determining protein-bound and intermediate uremic toxins in biological fluids. More specifically, the present invention relates to an optical method using fluorescence, preferably fluorescence of the consumed dialysate, and a specific model, including a unique set of optical spectral components at certain wavelengths to determine, preferably inline, the concentration. protein bound and intermediate uremic toxins such as beta2-microglobulin (b2m) and indoxyl sulfate (s). |