| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-84 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-09 |
| filingDate |
2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff5429af211fcd0c14dc545b11a430bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fac2fb11e4bb7029e99afb6b105cb084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d56a3c47c3ff11900fdfbb97b0a9af7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa3a6cc434a2208519ab71e40ea25508
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744ca685fefa5debb99cb9934e8fa0aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac068617280cb97d3dd90562d7fc059d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14008e2f2f8ec9a6cbd3cca1afe1a425 |
| publicationDate |
2015-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112012031959-A2 |
| titleOfInvention |
an improved process for preparing amisulpride |
| abstract |
an improved process for preparing amisulpride. The present invention relates to a novel process for the preparation of maisulpride (i) involving: methylation of 4-amino salicylic acid (vi) with dimethyl sulfate and a base, optionally in the presence of tbab to obtain -amino-2-methoxy-benzoate (viii) and (ii) the oxidation of 4-amino-2-methoxy-5-ethyl-thiobenzolic (ix) or 4-amino-2-methoxy-5-ethyl methylthio methyl benzoate (x) with the oxidizing agent in the presence of sodium tungstate or ammonium molybdate to give 2-methoxy-4-amino-5-ethylsulfonyl benzoic (iv) or 2-methoxy Methyl 4-amino-5-ethyl sulfonyl methyl benzoate (xi), respectively. |
| priorityDate |
2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |