http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112012028678-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19e9fae887a815be582e0a81d1832529 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34 |
filingDate | 2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75343472e952384c2e5071c4bb18fc26 |
publicationDate | 2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-112012028678-A2 |
titleOfInvention | oxidation process for preparing 3-formyl cefem derivatives |
abstract | Oxidation process for preparing 3-formyl cefem derivatives. The present invention relates to an improved process for oxidizing 3-hydroxymethyl-cephem derivatives to the corresponding 3-formyl-cephem derivatives. in particular, this oxidation process is for the preparation of 7- [2- (5-amino [1,2,4] thia-diazol-3-yl) -2-hydroxyimino-acetylamino] -3-formyl acid derivatives -8-oxo-5-thia-1-aza-bicyclo [4.2.0] oct-2-ene-2-carboxylic formula (i) using a combination of a 10-type hypervalent iodine oxidizing agent i-3 such as bis (acetoxy) iodo-benzene (baib) and a catalyst such as 2,2,6,6-tetramethyl-1-piperidinyloxy (time). These compounds of formula (I) are intermediates in the synthesis of ceftobiprol. |
priorityDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.