| abstract |
psmaxcd3 bispecific single chain antibody, its use and production process, as well as nucleic acid sequence, host cell and pharmaceutical composition. The present invention relates to a bispecific single chain antibody molecule comprising a first binding domain capable of binding a human epitope and a non-chimpanzee primate of the cd3 epsilon chain, wherein the epitope is part of a amino acid sequence comprised in the group consisting of seq id nos. 2, 4, 6 and 8, and a second binding domain capable of binding prostate specific membrane antigen (psma). the present invention also provides nucleic acids encoding said bispecific single chain antibody molecule, as well as vectors and host cells and a process for their production. the present invention further relates to pharmaceutical compositions comprising said bispecific single chain antibody molecule and medical uses of said bispecific single chain antibody molecule. |