| abstract |
pharmaceutical composition; and, use of composition. The present invention is directed to a composition useful for treating a faah-mediated disease, disorder or condition comprising a faah inhibitor and a second activation, comprising a selected faah imidazole or oxazole inhibitor and a second active agent. . the compositions will be useful in the treatment of a wide variety of disease, disorder, or conditions including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletal muscle pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, alzheimer's disease, and parkinson's disease. In another aspect, the invention disclosed herein is directed to compositions useful in the treatment of neuropathic and nociceptive pain, and said compositions comprise etoricoxib. |