| abstract |
therapeutic agent (y-39983) for corneal endothelial dysfunction. The present invention aims at a means for the effective and convenient treatment of diseases where corneal endothelial cells poor in terms of proliferative capacity in vivo are injured. The present invention provides a therapeutic agent for endothelial corneal dysfunction containing (r) - (+) - n- (1h-pyrrol [2,3-b] pyridin-4-yl) -4- (1-aminoethyl) benzamide or a pharmaceutically acceptable salt thereof (compound (la)) as active ingredient, an agent for promoting corneal endothelial cell adhesion containing compound (la), a culture medium for corneal endothelial cells containing the adhesion promoting agent , an implant for corneal endothelial keratoplasty, containing corneal endothelial cells, substrate and compound (la), and a method of producing a corneal endothelial preparation, including a step of culturing corneal endothelial cells using the culture medium. |