http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112012014519-A8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e673458c8c443e6fcd34bbc9565bf7f7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4743 |
| filingDate | 2010-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7938207377e73ad092f812296ff3ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4201daad6d00b6cee69e6a0016d50c14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fddaf61636c6a5203f8b4367d764fd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf0fc67e958cba9c9746a3c1fd9252d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77fea875dd1300a275d233a1342d38d5 |
| publicationDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-112012014519-A8 |
| titleOfInvention | tricyclic antibiotics |
| abstract | tricyclic antibiotic. compound of formula (I): wherein a1 represents -o-, -s- or -n-r3; a2 represents -ch-2 ~, -o-, -n-r4, -c (= o) -or -ch (o-r4) -; a 3 represents C 3-8 C 8 cycloalkylene; saturated and unsaturated 4- to 8-membered heterocyclodiyl having 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulfur, group a3 which is unsubstituted or substituted; a4 represents C 1 -C 4 alkylene, C 2 C 4 alkylene, C = o or a group selected from C 2 H 4 NH, C 2 H 4-s- being attached to the adjacent nr5- group via carbon atom; eg are aryl or heteroaryl which are unsubstituted or substituted and R 1 and R 2 independently represent hydrogen or a substituent selected from hydroxy, halogen, mercapto, cyano, nitro, C 1 -C 2. C6-6 alkyl, C6-6 alkoxy, C6-6 alkylthio, C6-6 alkylcarbonyloxy, C6-6 alkylsulfonyloxy, C 1-1 C 6 -heteroalkylcarbonyloxy, C 5- C 6 -heterocyclylcarbonyloxy, C 1-6 C 6 -heteroalkoxy, wherein the heteroalkyl, heteroalkoxy or heterocyclyl groups comprise 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulfur, substituents in which the alkyl moieties are unsubstituted or yet substituted; R3, R4 and R5 independently of one another represent hydrogen or C1-6 alkyl; x1 and x2 represent, independently of each other, a nitrogen atom or cr2, contact that at least one of x1 and x2 represents a nitrogen atom; m is 1; and the (ch2) m portion is optionally substituted by C1-4 alkyl; hydrogen, carboxy, hydroxy, C1-C4-alkoxy, C1-C4-alkylcarbonyloxy, amino, mono- or di-C1-C4-alkyl) amino or acylamino n is 0, 1 or 2 pharmaceutically acceptable salts thereof are valuable for use as a medicament for treating bacterial infections. |
| priorityDate | 2009-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.