abstract |
cyclic peptide, pharmaceutical composition, method for treating a disease, indication, condition or syndrome mediated by melanocortin receptor in a human or non-human mammal and method for treating a condition responsive to changes in melanocortin receptor function in a human mammal or non-human, these are cyclic peptides specific to the melanocortin receptor of formula (i) in which r1, r2, r3, r4, r5, r6, r7, r8 and r9 are as defined in the specification, the compositions and formulations include peptides of the preceding formula or salts thereof, and methods to prevent, ameliorate or treat melanocortin-1-mediated or responsive diseases, indications, conditions and syndromes. |