http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102016009542-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6bca44eb1bd3d2048be8425c2ec2afe |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C11-18 |
| filingDate | 2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_854fd7d703d27b63404ce33d8f165420 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a5b4bfc46e3409bbd058de63ddca94f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a1246dd2a4bdcb788387c7c71456b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60a0ed99414453d8817569f5d7386179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd7cc182f40622d4db3cec614dba9140 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a92265817ee03b7e62612e0b1ca46b1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2357e198a027a64345cabdd564a5a647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c527671ddd1bd568bdcc611a1c756624 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c79a0b3d6d676eb9d353918e5fa08ef2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdcec8bfa3bcb5eacd19dd5be763b7e4 |
| publicationDate | 2018-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102016009542-A2 |
| titleOfInvention | FORMULATION CONTAINING ALCOHOLIC MONOTERPENE AND B-CYCLODEXTRIN WITH ANALGESIC PROPERTY |
| abstract | formulation containing alcoholic monoterpene and analgesic property 1-cyclodextrin The present patent application relates to the formulation containing citronellol, an alcoholic monoterpene, and analgesic property i3-cyclodextrin. Chronic pain is pain that persists beyond the normal time of tissue healing, lasting more than three months, and is generally recognized as a public health problem, with important physical and psychological consequences. Despite the commercially available drugs, painful syndromes such as fibromyalgia or neuropathic pain still have ineffective treatment, high cost and undesirable side effects, which drives the pharmaceutical industry to search for medicines. Thus, in order to obtain new sources of analgesic drugs and reduce side effects, we aimed to study the effect of citronellol complexed on 3-cyclodextrin, administered orally in male swiss mice at doses of 12.5, 25 and 50 mg / kg and compare their effect to that of pure citronellol. Thus, it can be noted the analgesic effect of the formulation studied as superior to that of pure citronellol, as well as its mechanism of action through the glutamatergic, opioid and adrenergic pathway, without inducing tolerance, which makes the present formulation. an important alternative for analgesic treatment. |
| priorityDate | 2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.