http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102015018919-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc7845541ee383e44a7fdcaa02ef0dd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68d80933a35bd9437a0da03fd5bfb590 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8e306f2f95607b75bd928a5a2cd5be0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b944d402e26605d343a848045915eb79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e765452cf14a3a807ae8af646cb97f2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47bd2078f73ba1d28376abab4fb63982 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e27eb0b66f6676600a360929920ad646 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-69 |
filingDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43ad141e6f3dbfd24166d132b0196d1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb893f19fe997fd5ac1a938d0bfd3df5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbfd07e5d88383da1ddd233631d20b1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8372f76fcbaa696d1aa82b7e67a08f29 |
publicationDate | 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-102015018919-B1 |
titleOfInvention | Kit and method for testing dpd enzyme deficiency for patients being treated with fluoropyrimidines |
abstract | kit and method for testing dpd enzyme deficiency for patients being treated with fluoropyrimidines The present invention pertains to the technological sector of cancer chemotherapy and biochemical pharmacology and relates more specifically to a diagnostic test to determine the potential intolerance of a given patient to fluoropyrimidine class chemotherapy drugs. Composing the invention, there is the development of a kit for use in the dpd enzyme deficiency test, as well as a way of collecting, storing and transporting the sample of dry biological material on paper. the proposed kit allows the analysis of the toxicity of patients performing both saliva analysis. an individual risk rating is stipulated that the patient will present grades iii, iv and v toxicity in chemotherapy treatment with fluorpyrimidines. the advantages of the invention consist in the collection of only one biological sample to determine the concentrations of uracil (u) and dihydrouracil (uh2), as well as the stabilization of the concentrations of these dry substances on paper through the addition of gimeracil, which allows for non-refrigerated transport Sample. |
priorityDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.