http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102015014705-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac73ee5e8c91acf9c198babff125ce32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-47 |
| filingDate | 2015-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c81ada305b483a8efbe3b5bb98fab553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_373f2fc595d1a28a886377213d744a93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f2000f05f30eb0bb08d12db390d6763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f049876287dd6438cdddb658357dd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f264a85c4b1f96ac8cef9a8a569dad |
| publicationDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102015014705-B1 |
| titleOfInvention | delivery of hydroalcoholic extract of croton cajucara benth in an auto-emulsifying system for application in immunomodulatory therapy |
| abstract | hydroalcoholic extract of croton cajucara benth carried in an auto-emulsifying system with application in immunomodulating therapy microemulsified systems (sme) are an effective alternative to bioavailable drugs in liquid media. SMEs are thermodynamically stable colloidal solutions and can act as protective systems against enzymatic hydrolysis and as reservoirs for drugs, ensuring their slow and prolonged release. several studies have proven the increase in effectiveness and the reduction of toxicity of drugs (or active substances), of natural or synthetic origin, administered in this type of microparticulate structure. in the present invention, aiming to contribute to the pharmaceutical sector of phytotherapics, the hydroalcoholic extract (eha) obtained from the stem bark of the medicinal species croton cajucara benth (euphorbiaceae), was bioavailable, for oral use, in the colloidal meha system (auto-emulsifying system) containing the eha extract of C. cajucara). the colloidal system was prepared from a mixture of a nonionic surfactant and an oil phase containing coconuts nucifera l. (vegetable oil). the solubilization of the eha extract in this microemulsion resulted in the production of the phytotherapic meha, which has an antioxidant indication and is also being claimed to act in alternative therapies that favor the strengthening of the immune system. |
| priorityDate | 2015-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.