http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102014031535-A8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1de48d22dbff489a824ef99f8d8f9b6a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34dbe6a9e9ec14f1c798d2c5843c04c3 |
| publicationDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102014031535-A8 |
| titleOfInvention | pharmaceutical formulation and process for obtaining an oral solution containing praziquantel and oral solution containing praziquantel thus obtained |
| abstract | pharmaceutical formulation and process for obtaining a solution for oral use containing praziquantel and solution for oral use containing praziquantel thus obtained. the present invention patent is a pharmaceutical formulation and process for obtaining a solution for oral use containing praziquantel and product thus obtained, belonging to the technical area of drugs, which contains the active principle praziquantel, which is insoluble in water , indicated for the treatment or control of infestations by cestodes and / or trematodes in poultry and swine. for the treatment of farm animals, the product will subsequently be diluted in drinking water, and this formulation guarantees that the active ingredient praziquantel, which is practically insoluble in water, does not precipitate when it is diluted in a greater quantity of this universal solvent. the maximum recommended proportion for product dilution is up to 1 ml of the formulation in 100 ml of water. the present invention features a formulation and solution which preferably contain 1-15% praziquantel (w / v) and two organic solvents capable of dissolving the active principle. they are propylene glycol and formal glycerol. it also contains a surfactant (poloxamer), to reduce the adhesion of the product to the walls; a defoamer (simethicone emulsion); and two preservatives acting synergistically, methylparaben and propylparaben. |
| priorityDate | 2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.