http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102014024497-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_430e18d0c402d14ea89a2d3584b1a593 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K127-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-61 |
filingDate | 2014-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0f0d98429704bb2ae37be6aeb62cd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd9602b1893420b6f0b16a493503e2b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eb1f1126b69331b8da1a95a19f264a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e3346b6a4158d948486bfe77756a63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b1134a0fb2106f432104b7f2ce142b6 |
publicationDate | 2018-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-102014024497-A2 |
titleOfInvention | nanoemulsified compositions of fructose leucadendron and / or pilocarpine extract and / or fractions and uses |
abstract | nanoemulsified compositions of extract and / or fractions of ieucadendron tea tree and / or pilocarpine and uses. The present invention describes the obtainment of nanoemulsions with crude ethanolic extract from leucadendron and / or pilocarpine tea tree leaves and evaluations for potential use as a topical, antioxidant, anti-inflammatory and tissue regenerating radioprotector. These systems were prepared by phase inversion emulsification and duly characterized by measurements of mean particle diameter, polydispersion index and zeta potential. nanoemulsion without active and nanoemulsions with extract and / or pilocarpine were stable for 60 days, even after stressful conditions. concentrations below 500 µg / ml caused cytotoxicity below 20% and could be used without causing skin irritation. The formulations showed high antioxidant activity, with a ce50 of 18.7 µg / ml for those with nanoemulsified extract. |
priorityDate | 2014-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 314.