abstract |
pharmaceutical combination containing an analgesic agent and an antispasmodic agent, whose analgesic agent is tromethamine ketorolac which is physically isolated from the antispasmodic agent and whose antispasmodic active ingredient in combination with the ketorolac tromethamine analgesic agent is hyoscine, pargeverine, tolterodine, mebeverine or mebeverine, Papaverine. Both the ketorolac tromethamine analgesic agent and the antispasmodic agent are combined separately and for immediate release. The ketorolac tromethamine analgesic agent can also be found in the present combination in a separate and immediate release form, while the combined antispasmodic agent is in an equally separate but programmed release form. the ketorolac active ingredient of tromethamine is in a ratio of between 2.5% and 20% by weight and the antispasmodic active ingredient is in a ratio of between 2.5% and 20% by weight. |