| abstract |
zymomonas recombinant l-asparaginase. the present invention reports the construction and optimization of synthetic genes from the zymomonas mobilis l-asparaginase gene, its cloning and expression in escherichia coli. obtaining such an enzyme aims to produce high levels of a new l-asparaginase for use in pharmaceutical compositions based on l-asparaginase to be used. in the treatment of cancer, tumors, diseases with cell proliferation, as well as other medical applications. |