abstract |
Pharmaceutical compositions based on divalent ruthenium derivatives and use thereof Divalent ruthenium derivative pharmaceutical compositions are described, compositions comprising: a) compounds of formula [ru (aa) (no) (pp) (nn)] x where the ru (ll) ion is combined with an amino acid, phosphines and bipyridine derivatives, and where x is the phosphorus hexafluoride ion, chloride, acetate and nitrate, in addition to diimine and phosphine binders and b) a pharmacologically acceptable carrier. Also described is the use of the compositions of the invention in a medicament for treating cancer. |