| abstract |
hsp 83-1 recombinant leishmania protein for use in leishmaniasis vaccine The present invention relates to the recombinant hsp 83-1 antigen, a protein present in protozoa of the genus leishmania, and its use in the production of human and / or leishmaniasis vaccines. Dogs. This antigen was selected by bioinformatics analysis, involving immunoproteomics and phylogeny algorithms. The elisa reaction with anti-hsp 83-1 antibodies showed that there is recognition of the recombinant protein produced by mouse serum, indicating that hsp 83-1 is an important candidate for leishmaniasis vaccine antigen. |