http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102013026570-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f861d7dfdde7b233339d4838364a8e8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 2013-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8014ab1d7498e0bc4d572fba2cff727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_522d7d8a0940bcb3b0d0c4bfbc58462d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9d603226b3c8570bc0655838064ff9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f8f7d3526d2f112d4f75fc3761ee196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4047e2635a705b6297ffdb94fd7f5721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_265f78345956e142d8156f17365525f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_964e3187438315b13fadd9352fc86ca6 |
| publicationDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102013026570-A2 |
| titleOfInvention | recombinant chimeric protein, immunogenic composition, production process, use for the production of vaccines and sera against the bite of loxosceles spp |
| abstract | recombinant chimeric protein, immunogenic composition, production process, use for the production of vaccines and sera against the bite of spiders loxosceles spp. The present invention relates to a chimeric protein and the immunogenic composition containing it and may comprise carriers such as liposomes which confer increased efficacy and specificity in the production of serum and vaccine. The technology also addresses the process of obtaining recombinant chimeric protein containing epitopes obtained from sphingomyelinase d protein, brown spider venom (loxosceles intermedia), its linear structural form and its three-dimensional arrangement and the use of this protein in vaccine production and serum against the brown spider bite. The rcpli chimera was nontoxic when injected in horses, increasing their life span and generating immunoglobulins capable of neutralizing the dermonecrotic and hemolytic effects caused by brown spider venom. Finally, the invention comprises the use of protein and immunogenic composition for the treatment and prevention of loxoscelism. |
| priorityDate | 2013-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 447.