http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102013012934-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68d80933a35bd9437a0da03fd5bfb590 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb8ef1d9e8fa3eb51aef28db34d4b2bd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a9f07393d47793c13fa958a8ee95999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63931db9cbc422a59b85c3e0fcfe5c83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55205dd9db402c09d1febf5a152b2355 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_060d47b35135b38b8e4c1151f328e113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95a1cbe6c3569785e1a459282fd3c0b4 |
| publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102013012934-B1 |
| titleOfInvention | MULTI-COMPONENT PROCESS FOR SYNTHESIS OF FATTY DERIVATIVES OF Y-AMINOBUTYRIC ACID (GABA) FOR PHARMACOLOGICAL PURPOSES AND PRODUCTS |
| abstract | MULTI-COMPONENT PROCESS FOR SYNTHESIS OF FATTY DERIVATIVES OF GAMMA-AMINOBUTRIC ACID (GABA) FOR PHARMACOLOGICAL PURPOSES AND PRODUCTS The present invention describes a process for obtaining derivatives of gamma-aminobutyric acid (GABA) from the multicomponent synthesis of nitroesters as advanced synthetic intermediates. for obtaining the gamma-amino acids. It is also the object of this invention, using the same process, the synthesis of new analogues of gamma-aminobutyric acid, beta-alkyl substituted with fatty chains consisting of four to twenty-two carbons (C4-C22), saturated, unsaturated and polyunsaturated, aiming at increasing of the lipophilicity of GABA analogues. The synthesis of nitroesters occurs through a multicomponent reaction in good yields with a simple and direct procedure, performed in a single step involving the condensation of aliphatic aldehydes (fatty) with Meldrum acid, nitromethane and ethanol or methanol in the presence of bifunctional catalysts. . |
| priorityDate | 2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.