| abstract |
Carbon nanotube-based antitumor vaccine formulation and use The present invention describes carbon nanotubes functionalized with acid oxygen groups, having at least one tumor antigen coupled to them, preferably from the 'cancer / testis' family, their preparation process and their preparation process and its use in antitumor vaccine formulations. In addition, at least one toll-like receptor agonist can be coupled to these carbon nanotubes, which has potent immunostimulatory activity. This vaccination strategy can be used to treat diseases, such as cancer, which require induction of a cell-mediated and antibody-specific immune response. |