http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102012031182-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd3e120e7d6535b615889314b0d2d6b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8e7cb5a043c5fc4ef0517627385e699 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9211f207af61ebf0b0d355251dad1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a39a3dca76c388edbc942ee7082ea09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1259daecc803a0977e7bca375a91ece3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa5e2dab65234515b209abad0ca43385 |
| publicationDate | 2014-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102012031182-A2 |
| titleOfInvention | DNA SEQUENCES, KIT AND USE FOR TP53 R337H MUTATION DETECTION |
| abstract | DNA SEQUENCES, KIT AND USE FOR DETECTING TP53 R337H MUTATION The present invention is about DNA sequences, kit containing such sequences and use for the detection of the TP53 R337H mutation. More specifically, the present invention is about DNA sequences, a kit and use that allow the genotyping of alleles by Real Time POR (or RQ-PCR), eliminating the post-reaction steps of POR. The TP53 R337H mutation is related to different types of cancer, such as adrenal cortex tumor (ACT), choroid plexus carcinoma (OPO), prevalent in children in the South and Southeast of Brazil, osteosarcoma, prevalent in children and adolescents, and breast cancer, prevalent in adults. In particular, TCA and OPO are potentially fatal malignant tumors. The present invention allows samples to be evaluated by RO-POR, which eliminates post-POR treatment steps, thus reducing the time spent and the reagents used. In addition, the present invention allows for analysis and pooled samples, allowing a greater number of patients to be evaluated for the presence or absence of the mutation at the same time, generating scalability for detecting the given mutation. |
| priorityDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.