http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102012008099-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f5fe457ac6ff77af2e7632298a0a475 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 |
| filingDate | 2012-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f0824566d7e4a31c0039a50fec96ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59499e563a82ab936ad861944b68bce1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14242544259a50ee908d815a401fabb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10d3eb7b8a22a2bbd52707625b287bea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd0d028a2b54d865f0db35005c4ac541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29a736e0d247f330f04e2d081246ef7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3b960785d2e54f021f1e32134c05516 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6472271add961b4da147409181f3eb6c |
| publicationDate | 2013-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102012008099-A2 |
| titleOfInvention | USEFUL COMPOUNDS IN ALZHEIMER'S DISEASE THERAPY ISOLATED BY CITRUS LIMON AND ITS APPLICATIONS IN PHARMACEUTICAL FORMULATIONS |
| abstract | USEFUL COMPOUNDS IN CITRUS LIMON ISOLATED ALZHEIMER'S DISEASE THERAPY AND THEIR APPLICATIONS IN PHARMACEUTICAL FORMULATIONS The present invention relates to coumarins isolated from Citrus limon (L.) Burm with potential application as acetylcholinesterase enzyme inhibitors and methods for obtaining them. . Said coumarins may be of use in the treatment of alzheimer's disease, and may be administered as conventional pharmaceutical formulations or as controlled / modified release transdermal preparations. The present invention relates more precisely to the isolation of the mixture of curamines [5,8-dimethoxypsoralen and 5,7-dimethoxycoumarin] present in the ethyl acetate (ACOET) fraction of the ethanolic extract of the leaves of the C. limon plant ( L.) Brun and its application in the technological development of pharmaceutical forms for the prevention and / or treatment of Alzheimer's disease, a disease associated with the reduction of brain neurotransmitters, especially acetylcholine. |
| priorityDate | 2012-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.