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publicationDate 2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-102012003901-A2
titleOfInvention optical device for detection of specific marker of cardiac injury
abstract The present invention relates to the manufacture of an optical device capable of detecting troponin macromolecule t which has a direct relationship with the cardiac lesion. The device is composed of a laser source that focuses a bioelectrode that becomes luminescent after recognizing the specific marker of cardiac injury. a photomultiplier coupled to a spectrometer amplifies this signal, which in turn is acquired by interfacing with a specific software whose output is expressed as luminescence in the form of a Gaussian curve where the peak is related on the abscissa axis with the characteristic wavelength of fluorophores. consisting of quantum dots and the ordinate axis with the concentration of troponin t. The making of the bioelectrode is made possible by modifying a vitreous electrode with a translucent polymeric film that covalently binds to the anti-troponin t antibody. Selective recognition of the troponin t heart injury marker by this bioelectrode is indirectly indicated by luminescence emission after additional high specificity couplings and can thus be used for diagnostic purposes.
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