http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102012002469-A2

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-40
filingDate 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd968a8873bc0614c9821d0ed7c1b4b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3980d76c47bad9467c801c258056db45
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publicationDate 2015-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-102012002469-A2
titleOfInvention Recombinant multiepitope protein, its procurement process and its applications related to rubella
abstract Recombinant multiepitope protein, its procurement process and its applications related to rubella. This invention relates to a recombinant, especially biotechnologically engineered recombinant antigenic protein, containing different most prevalent rubella virus epitopes or regions most representative in Brazil and worldwide. It is a multiepitope protein containing appropriately sized flexible connectors to facilitate the connection between different epitopes or viral fragments. This structural feature gives the protein greater sensitivity and specificity in recognizing anti-rv antibodies. In addition, the multiepitope protein induces a broader immune response desirable for the treatment of different applications related to rubella detection, immunization, prevention and treatment; This makes it useful in the preparation of different products of interest to the pharmaceutical and biotechnology industries, such as in vitro diagnostic kits for the detection of rubella from physiological samples of humans, as well as immunogenic compositions, vaccines, medicines or biopharmaceuticals. prevent and treat this disease. Additionally, as an input for the production of monoclonal antibodies. Another aspect of the present invention is related to the process of obtaining such a protein based on cloning and heterologous expression in microorganisms.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020113303-A1
priorityDate 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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