http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102012002469-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7c17dba509c1efd3a166bf9f7b3dd24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_486383bcdc108830b08d6478134bae03 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-40 |
filingDate | 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd968a8873bc0614c9821d0ed7c1b4b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3980d76c47bad9467c801c258056db45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8452fea0c28e45f75b9ff19b7f2a7ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23f5da5a46bdc8bc1ac8dd06a5b082b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf18787379c63f8212ab1e72e91ef063 |
publicationDate | 2015-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-102012002469-A2 |
titleOfInvention | Recombinant multiepitope protein, its procurement process and its applications related to rubella |
abstract | Recombinant multiepitope protein, its procurement process and its applications related to rubella. This invention relates to a recombinant, especially biotechnologically engineered recombinant antigenic protein, containing different most prevalent rubella virus epitopes or regions most representative in Brazil and worldwide. It is a multiepitope protein containing appropriately sized flexible connectors to facilitate the connection between different epitopes or viral fragments. This structural feature gives the protein greater sensitivity and specificity in recognizing anti-rv antibodies. In addition, the multiepitope protein induces a broader immune response desirable for the treatment of different applications related to rubella detection, immunization, prevention and treatment; This makes it useful in the preparation of different products of interest to the pharmaceutical and biotechnology industries, such as in vitro diagnostic kits for the detection of rubella from physiological samples of humans, as well as immunogenic compositions, vaccines, medicines or biopharmaceuticals. prevent and treat this disease. Additionally, as an input for the production of monoclonal antibodies. Another aspect of the present invention is related to the process of obtaining such a protein based on cloning and heterologous expression in microorganisms. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020113303-A1 |
priorityDate | 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.